The impact of heparin on Hb levels during blood gas analysis in critical patients
Keywords:
Hb level, Heparin, Blood gasAbstract
Laboratory anticoagulants are acidic, resulting in a fall in blood hydrogen potential (pH), increased plasma oxygen (PO2) levels, and reduced hemoglobin levels. This study intends to assess the difference in hemoglobin levels between blood gas analysis (BGA) examinations performed with sodium heparin and lithium heparin anticoagulants utilizing Ethylene Diamine Tetraacetic Acid (EDTA) anticoagulants. Analytical observational research was performed on sixty samples of hemoglobin concentration test findings on BGA examination of arterial patients who were not receiving anticoagulant medication. Statistical analysis obtained the differences in hemoglobin concentrations examined using anticoagulants sodium heparin with EDTA (p-value = 0.000). Hemoglobin concentrations were examined using anticoagulants lithium heparin with EDTA (p-value 0.002). There was a substantial difference in the assessment of hemoglobin concentration with sodium and lithium heparin anticoagulants and with EDTA anticoagulants. The final concentration of heparin blood and dilution in the blood is the result of selecting anticoagulant kinds and quantities. Thus, it must be taken into account when collecting blood samples because it affects laboratory test findings.
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